by michaelhalassa | Jun 12, 2025 | Cognitive flexibility, Cognitive Processing, Michael Halassa, Neural circuits, NeuroAI
An Elegant Natural Experiment The study by Mackenzie et al. (2025, bioRxiv) represents a particularly clever approach to understanding human thalamic function. Rather than relying on correlational neuroimaging, the researchers capitalized on an unintended consequence...
by michaelhalassa | Apr 13, 2025 | Cognitive flexibility, Computational neuroscience, Halassa Lab, Mediodorsal thalamus, Neural circuits, NeuroAI, Prefrontal cortex, Schizophrenia research, Thalamocortical circuits, Working memory
In our ongoing quest to understand how the brain enables flexible cognition, the mediodorsal (MD) thalamus and its dialogue with the prefrontal cortex (PFC) have emerged as central players. Following a series of modeling papers from our lab—including Wei-Long Zheng’s...